My background in ecology and evolution has strongly influenced my research interests. The broad questions on processes and interactions within evolutionary systems are what interest me most. Modern high-throughput sequencing is an excellent tool to explore natural variation since it provides unparalleled resolution into the evolutionary process. While my undergraduate studies focused on organismal evolution and ecology, my postgraduate studies sparked my interest in investigating the evolutionary process on a microscopic scale. My postgraduate experience is now providing me insight into evolution within an organism when looking at the genesis and evolution of cancer within a patient.
My research interests are now also underpinned by an enjoyment for writing software and creating tools for others to use. This has involved the sole development of, and contribution to, many internal and external pipelines, tools and platforms.
Gayevskiy, V. & Roscioli, T. & Dinger, M.E. & Cowley, M.J. (2018). Seave: a comprehensive web platform for storing and interrogating human genomic variation. bioRxiv (preprint). DOI: 10.1101/258061 | PDF
De Sousa, S.M. & McCabe, M.J. & Wu, K. & Roscioli, T. & Gayevskiy, V. et al (2017). Germline variants in familial pituitary tumour syndrome genes are common in young patients and families with additional endocrine tumours. European Journal of Endocrinology, 176 (5), pp. 635-644. DOI: 10.1530/EJE-16-0944 | PDF
Balasubramaniam, S. & Riley, L.G. & Vasudevan, A. & Cowley, M.J. & Gayevskiy, V. & Sue, C.M. & Edwards, C. & Edkins, E. & Junckerstorff, R. & Kiraly-Borri, C. & Rowe, P. & Christodoulou, J. (2017). EPG5-Related Vici Syndrome: A Primary Defect of Autophagic Regulation with an Emerging Phenotype Overlapping with Mitochondrial Disorders. JIMD Reports. DOI: 10.1007/8904_2017_71 | PDF
Balasubramaniam, S. & Riley, L. & Bratkovic, D. & Ketteridge, D. & Manton, N. & Cowley, M.J. & Gayevskiy, V. & Roscioli, T. & Mohamed, M. & Gardeitchik, T. & Morava, E. & Christodoulou, J. (2017). Unique presentation of cutis laxa with Leigh-like syndrome due to ECHS1 deficiency. Journal of Inherited Metabolic Disease, 40 (5), pp. 745-747. DOI: 10.1007/s10545-017-0036-4 | PDF
Riley, L.R. & Cowley, M.J. & Gayevskiy, V. et al (2016). A SLC39A8 variant causes manganese deficiency, and glycosylation and mitochondrial disorders. Journal of Inherited Metabolic Disease, 40 (2), pp. 261-269. DOI: 10.1007/s10545-016-0010-6 | PDF
Heimer, G. et al. (2016). MECR Mutations Cause Childhood-Onset Dystonia and Optic Atrophy, a Mitochondrial Fatty Acid Synthesis Disorder. The American Journal for Human Genetics, 99 (6), pp. 1229-1244. DOI: 10.1016/j.ajhg.2016.09.021 | PDF
Gayevskiy, V. & Lee, S. & Goddard, M.R. (2016). European derived Saccharomyces cerevisiae colonisation of New Zealand vineyards aided by humans. FEMS Yeast Research, 16 (7), fow091. DOI: 10.1093/femsyr/fow091 | PDF
Merlevede, J. et al. (2016) Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents. Nature Communications, 7:10767 DOI: 10.1038/ncomms10767 | PDF
Gayevskiy, V. & Goddard, M.R. (2016) Saccharomyces eubayanus and Saccharomyces arboricola reside in North Island native New Zealand forests. Environmental Microbiology, 18 (4), pp. 1137-1147. DOI: 10.1111/1462-2920.13107 | PDF
Rogers, S. & McCloy, R. & Parker, B. & Chaudhuri, R. & Gayevskiy, V. & Hoffman, N. & Watkins, D. & Daly, R. & James, D. & Burgess, A. (2015). Dataset from the global phosphoproteomic mapping of early mitotic exit in human cells. Data in Brief, 5, pp. 45-52. DOI: 10.1016/j.dib.2015.08.010 | PDF
McCloy, R. & Parker, B. & Rogers, S. & Chaudhuri, R. & Gayevskiy, V. & Hoffman, N. & Ali, N. & Watkins, N. & Daly, R. & James, D. et al (2015). Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation Motifs. Molecular and Cellular Proteomics, 14 (8), pp. 2194-2212. DOI: 10.1074/mcp.M114.046938 | PDF
Gayevskiy V. & Klaere S. & Knight S. & Goddard M.R. (2014) ObStruct: A Method to Objectively Analyse Factors Driving Population Structure Using Bayesian Ancestry Profiles. PLoS ONE, 9 (1): e85196. DOI: 10.1371/journal.pone.0085196 | PDF
Gayevskiy, V. & Goddard, M.R. (2012). Geographic delineations of yeast communities and populations associated with vines and wines in New Zealand. ISME Journal, 6 (7), pp. 1281-1290. DOI: 10.1038/ismej.2011.195 | PDF
2016 - AGTA Conference Poster
2015 - AGTA Conference Poster
2014 - NZMEC Symposium Talk
2014 - NZ Phylogenomics Meeting Talk
2011 - Romeo Bragato Conference Talk
2010 - New Zealand Microbiological Society (NZMS) Conference Talk
2017 - Taught the sections on cancer genomics, bioinformatics for clinicians, introduction to Seave and copy number/structural variants at the Clinical Genomics Workshop hosted by the Kinghorn Centre for Clinical Genomics in Hong Kong. Ran two practical workshop sessions on using Seave to diagnose patients with rare disease and validate variants using IGV.
2016 - Taught the copy number variation and variant filtration sections of the Cancer Genomics Workshop hosted by BioPlatforms Australia in Melbourne.
2015 - Taught the copy number variation and variant filtration sections of the Cancer Genomics Workshop hosted by BioPlatforms Australia in Canberra.
2015 - Short talk on Seave at the Clinical Genomics workshop hosted at the Kinghorn Centre for Clinical Genomic.s